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  • Team

    Team

  • Team

    Team

  • Team

    Team

Alumni

Staff alumni

Staff alumni

Laura van Eyndhoven

Year: 2023
Position: PhD student
Thesis/project title: Decoding type I interferon response dynamics using microfluidics and modeling

Nikita Subedi

Year: 2022
Position: PhD student
Thesis/project title: Decoding functional heterogeneity in immune cells: New avenues for immunotherapy

Nidhi Sinha

Year: 2022
Position: PhD student
Thesis/project title: Single Cell Approach Towards Immune Signaling Dynamics

Erin M. O'Brien

Year: 2022
Position: PhD student
Thesis/project title: Zooming in on macrophage plasticty and T cell interactions
Role/additional info: Guest researcher from Kara Spiller Lab, Drexel University

Catarina Matos

Year: 2021
Position: Laboratory technician

Annelies Wauters

Year: 2021
Position: PhD student
Thesis/project title: Shaping Polymeric Nanocarriers for Immunotherapy

Moniek Looijenga

Year: 2020
Position: Secretary

Eleni Chouri

Year: 2020
Position: Postdoctoral researcher
Thesis/project title: Unraveling IFN-I response dynamics in the pathophysiology of systemic lupus erythematosus

Yu Zhao

Year: 2019
Position: Postdoctoral researcher
Thesis/project title:  Development of Smart Nanogel Vaccines against Bacterial Toxins
Role/additional info: Guest researcher from Tang Lab, École Polytechnique Fédérale de Lausanne (EPFL)

Jorieke Weiden

Year: 2019
Position: PhD student
Thesis/project title: Synthetic immune niches for localized cancer therapy
Role/additional info: Co-promotor, Radboudumc - Tumor Immunology

Loek J Eggermont

Year: 2018
Position: PhD student
Thesis/project title: A synthetic dendritic cell platform for immune activation
Role/additional info: Co-promotor, Radboudumc - Tumor Immunology

Florian Wimmers

Year: 2017
Position: PhD student
Thesis/project title: Probing functional cellular heterogeneity using single cell technology: implications for immunotherapy
Role/additional info: Co-promotor, Radboudumc - Tumor Immunology

Simone Sittig

Year: 2016
Position: PhD student
Thesis/project title: Human blood dendritic cell subsets pinpointing the most potent subset for dendritic cell-based cancer immunotherapy
Role/additional info: Co-promotor, Radboudumc - Tumor Immunology
Student alumni

Student alumni

Evelien van der Linden

Year: 2023
Position: Bachelor student
Thesis/project title: Investigation of cytokine secretion in Jurkat T-cells with droplet microfluidics and bulk analysis

Thomas van de Kreeke

Year: 2022
Position: Master Student
Thesis/project title: Temporal perturbation of STAT1/2 activities reveal dynamic ligand discrimination of type I interferon signalling

Chantal Vreezen

Year: 2022
Position: Master Student
Thesis/project title: Collaboration to success: quorum sensing in type i interferon response dynamics of plasmacytoid dendritic cells

Maarten van Zon

Year: 2022
Position: Master Student
Thesis/project title: The effect of a microfluidics-generated ‘artificial PCM’ on chondrocyte phenotype and matrix production

Sebastiaan Heester

Year: 2022
Position: Master Student
Thesis/project title: Dissecting the IL-10 feedback loop present in a small population within pro infammatory stimulated macrophages

Jo-Anne Ewald

Year: 2022
Position: Bachelor student
Thesis/project title: Studying the ability of plasmacytoid dendritic cells to produce interleukin-10 and its potential effect on Interferon-alpha and Tumor-Necrosis-Factor-alpha

Damla Metindogan

Year: 2022
Position: Bachelor student
Thesis/project title: The effect of the PI3K/Akt/mTOR pathway on the IFNα production in pDCs

Myrthe Kapteijns

Year: 2022
Position: Bachelor student
Thesis/project title: The influence of Trichostatin A on the cell fate of first and second versus non-responder of in bulk activated pDCs focusing on IFN-I production

Carolien Verbiest

Year: 2022
Position: Bachelor student
Thesis/project title: The effect of epigenetic modifications on IFN-I production by human plasmacytoid dendritic cells

Nouaman Ljamâi

Year: 2022
Position: Bachelor student
Thesis/project title: The effect of interferon beta double-pulse stimulation on STAT1/2 activation dynamics

Shanna Edelenbosch

Year: 2022
Position: Bachelor student
Thesis/project title: Temporal STAT1/2 activities in single cells under double-pulse IFNα stimulation

Jesse Hulleman

Year: 2022
Position: Bachelor student
Thesis/project title: Cytotoxic T-cell activation at the bulk and single-cell level

Emily Valentine

Year: 2022
Position: Guest Student

Ashley Sturtewagen

Year: 2022
Position: Internship student
Thesis/project title: IL-10 secreting macrophages shows an anti-inflammatory feedback in bulk stimulation of LPS in a density hydrogel experiment and in combination with cytokines

Robin van den Dungen

Year: 2022
Position: Internship student
Thesis/project title: Characterization of interferon gene s¡gnatures and interferon secretion dynamics on TNFα and lFNα

Vincent Verberne

Year: 2021
Position: Master Student
Thesis/project title: Decoding heterogeneity: drivers of first responding cells in type 1 interferon response

Choi Ha Hyun

Year: 2021
Position: Bachelor student
Thesis/project title: A quantitative study on the expression of CD56 on IL-4, IL-15, and IFN-α monocyte derived dendritic cells

Kirsten Brusse

Year: 2021
Position: Bachelor student
Thesis/project title: Cytotoxic capabilities of moDCs

Freek Blanke

Year: 2021
Position: Bachelor student
Thesis/project title: Macrophage anti- and pro-inflammatory balance for homeostasis; a potential role for immune evasion in the tumor microenvironment

Kaylee de Jong

Year: 2021
Position: Bachelor student
Thesis/project title: Hydrogel droplets in microfluidics as a tool for dissecting cellular heterogeneity; novel applications for understanding immunologic interactions

Laurian de Vries

Year: 2021
Position: Bachelor student
Thesis/project title: CD56, CD11c, and CCR7 expression in stimulated monocyte-derived dendritic cells

Mark Sweep

Year: 2020
Position: Master Student
Thesis/project title: Studying macrophage polarisation in health and in cancer using a single-cell, adherent cell culture method

Vera Koomen

Year: 2020
Position: Master Student
Thesis/project title: Optimization of droplet-based microfluidic assays to study immune cells at single-cell level

Dennis Verkooijen

Year: 2020
Position: Master Student
Thesis/project title: Evaluating the effect of polymersome morphology on cytotoxicity and cellular uptake

Ayla Hokke

Year: 2020
Position: Master Student
Thesis/project title: High-throughput droplet-based microfluidic assay to study single-cell cytotoxicity in real time

Justin Lebens

Year: 2020
Position: Master Student
Thesis/project title: Mathematical modeling of type I and type II interferon pathways for decoding single cell immune dynamics Activities of STAT1 in response to dynamic interferon stimulation

Gilles Berntsen

Year: 2020
Position: Master Student
Thesis/project title: Sex differences in the human macrophage response to resorbable synthetic biomaterials in vitro

Lars Houben

Year: 2020
Position: Master Student
Thesis/project title: A droplet-based platform for assessing NK cell mediated cytotoxicity in real time

Luc Hendriks

Year: 2020
Position: Master Student
Thesis/project title: Length-dependent activation of RIG-I and MDA5 by viral dsRNA and its effect on the immune response generation in NIH/3T3 fibroblasts analyzed at a single-cell level

Laura Ritter

Year: 2020
Position: Master Student
Thesis/project title: Live monitoring of single plasmacytoid dendritic cell survival

Tanja Ypma

Year: 2020
Position: Master Student
Thesis/project title: The detection of circulating tumor cells based on the Warburg effect using droplet-based microfluidics

David Janse

Year: 2020
Position: Master Student
Thesis/project title: Numerical modelling and simulation of microfluidic large scale. integration device

Lynn C.E. Bongaerts

Year: 2020
Position: Bachelor student
Thesis/project title: NKg2A, NKp46 and NKg2D expression on heterogeneous NK cells

Thomas van de Kreeke

Year: 2020
Position: Bachelor student
Thesis/project title: Expression of CCR7, CD107a and CD2 in relation to NK cell heterogeneity

Ilse van Roessel

Year: 2020
Position: Bachelor student
Thesis/project title: The influence of tumor cells and the tumor microenvironment on the heterogeneity of natural killer cells

Esmée Bosman

Year: 2020
Position: Bachelor student
Thesis/project title: Heterogeneity of tissue-resident natural killer cells

Kjell Steps

Year: 2019
Position: Master Student
Thesis/project title: The influence of cell-cell and cell-matrix interactions on the polarization of macrophages

Laura Links

Year: 2019
Position: Bachelor student

Sarah van der Weerd

Year: 2019
Position: Bachelor student
Thesis/project title: Influence of IL-15 on the interferon gamma production of NK 92 cells

Josja Veul

Year: 2019
Position: Bachelor student
Thesis/project title: The difference in the amount of INF-y production between single cells and cells in bulk, when stimulated by IL-12

Hanna Merényi

Year: 2019
Position: Bachelor student
Thesis/project title: The effect of cell-cell contact on the activation of NK-92 cells to produce IFN-γ when stimulated with IL-18

Bart Tiemeijer

Year: 2018
Position: Master Student
Thesis/project title: Probing macrophage plasticity and heterogeneity using microfluidic single-cell encapsulation and multicolor flow cytometry

Kwankwan Zhu

Year: 2018
Position: Master Student
Thesis/project title: Detection of circulating tumor cells using pH-responsive antibodies and droplet-based microfluidics

Roderick Verberne

Year: 2018
Position: Bachelor student
Thesis/project title: Decoding cellular communication using droplet based microfluidics

Vincent Verberne

Year: 2018
Position: Bachelor student
Thesis/project title: Multiple cell encapsulation in microfluidic droplets

Luc Hendriks

Year: 2018
Position: Bachelor student
Thesis/project title: Characterization of 3-inlet droplet microfluidic device for single and multiple cell encapsulation

Dennis Verkooijen

Year: 2018
Position: Bachelor student
Thesis/project title: Decoding cellular communication using droplet based microfluidics

Ayla Hokke

Year: 2018
Position: Bachelor student
Thesis/project title: The characterization of a three-inlet droplet microfluidic device

Vera Koomen

Year: 2017
Position: Bachelor student
Thesis/project title: Determination of heterogeneity by comparing the cytokine secretion of single Jurkat T-cells to the bulk population

Tim Voermans

Year: 2017
Position: Bachelor student
Thesis/project title: Heterogeneity of Jurkat cells during bulk stimulation by different PHA concentrations

Tamara Labeur

Year: 2017
Position: Bachelor student
Thesis/project title: Determine heterogeneity and the effect of different concentrations stimuli on the secreted IFN-γ cytokine of Jurkat T-cells

Riv Maas

Year: 2017
Position: Bachelor student
Thesis/project title: Determine heterogeneity and the effect of different concentrations stimuli on the secreted IFN-γ cytokine of Jurkat T-cells